second-liners meaning: → secondaries. How to see if your second payment is still on the way, why some may … adjective Relating to or being a secondary stage of something. ; adjective Being a drug or therapy that is used to treat a condition or disease only after another drug or therapy has been used or considered. Second-line chemotherapy is now accepted as a standard and should be offered to patients with good performance status and failing platinum-based first-line chemotherapy. Second-line therapies are those tried when the first ones do not work adequately. Define second-line. Some second mortgages are “open-end” (meaning you can continue to take cash out up to the maximum credit amount and, as you pay down the balance, can draw again up to the same limit) and other second mortgage loans are “closed-end” (in which you receive the entire loan amount … Second-lien debt is borrowing that occurs after a first lien is already in place. The management of a cancer case requires regular evaluation of treatment and adjustment as needed. usually in New Orleans. Second-line chemotherapy refers to a range of medications available to people whose disease has spread or recurred despite initial treatment. Copyright © 2010 by Houghton Mifflin Harcourt. Second-line supervisors establish a liaison for senior management and first-line supervisors as a foundation for a company. Second-line treatment is treatment for a disease or condition after the initial treatment ( first-line treatment) has failed, stopped working, or has side effects that aren't tolerated. 2. from The American Heritage® Dictionary of the English Language, 5th Edition. The second line of defense consists of separately established risk, control, and compliance oversight functions that ensure properly designed processes and controls are in place within the first line of defense and are operating effectively. The newly married couple leads the second line holding uniquely decorated umbrellas or parasols. 1. It's important to understand "lines of treatment" and how they differ from first line treatment and can play a … Usually, the second line brings the wedding guests and bridal party from the ceremony to the reception. It subsequently refers to the ranking of the debt in the event of a … In the real world, however, a single line of defense often can prove inadequate. Although the second lien loan's security interest is subordinated to the first lien loan's interest in the pledged assets of the company, the ranking of first lien and second lien loans are the same in the event the pledged assets are not sufficient to satisfy the outstanding borrowings. US. The specific functions will vary by organization and industry, but typical functions in this second line of defense include: The cells involved are white blood cells (leukocytes), which seek out and destroy disease-causing organisms or substances.There are different types of leukocytes. First- and second-line drugs, minimum inhibitory concentrations (MICs) and mechanisms of drug resistance are presented in Table 1 . The second line of defence involves specialist cells and white blood cells such as phagotcytes, macrophages, neutrophils, natural killer cells, dendritic cells, complement proteins and mast cells. NCI's Dictionary of Cancer Terms provides easy-to-understand definitions for words and phrases related to cancer and medicine. Treatment may also extend a patient’s life, but second-line chemotherapy is rarely curative. Antituberculosis drugs are mainly divided into two parts. 1 usually as modifier A medical treatment or therapy used in support of another, or as a more drastic measure if the primary treatment is ineffective. [ From the second line formed by people who, joining the traditional funeral parades of New Orleans after being attracted by the music, sing and dance while following the first line that includes the hearse, the family and friends of the deceased, and the band.] ‘second-line, expensive, often invasive tests’. The History of Beads at Second Line (and Mardi Gras) Parades: The throwing of trinkets to the crowds of Mardi Gras was started in the 1870’s by the Twelfth Night Revelers, and is a time-honored expectation of young and old alike. second-line synonyms, second-line pronunciation, second-line translation, English dictionary definition of second-line. Top definition. The responsibilities of these second-line functions typically include participating in the business unit’s risk committees, reviewi… Rather, they focus on solving problems that need in-depth knowledge about your products and services. They are dispensable, rather like pawns on a chessboard. Second line agents are more specialist in their knowledge. Home equity loans and home equity lines of credit (HELOCs) are common examples of second mortgages. A break with the primary treatment and an adoption of a new regimen signals “second-line treatment.” Management establishes various risk management and compliance functions to help build and/or monitor the first line-of-defense controls. Learn more. Evidence is in favour of docetaxel and in the case of adenocarcinoma and adequate renal function, pemetrexed is recommended. We also service Diebold, Triton, Tranax, Hyosung and other tier-one ATM products. ATM Second Line Maintenance Services NCR has more than 13,000 service professionals that are connected to our extensive hardware maintenance network with customer care centers around the world. Many couples opt to add a grand marshal, an energetic local who heads the parade. Here's what to know now that the IRS has stopped sending stimulus checks. noun. American Heritage® Dictionary of the English Language, Fifth Edition. It signifies the beginning of a new life together. All rights reserved. All of the guests who want to join in the celebration make up the second line. Discover the history and tradition of the second line in New Orleans with GoNOLA TV! Webster’s New World College Dictionary, 4th Edition. Those who follow the band just to enjoy the music are called the "second line." ‘Another review of several case studies recommended oral and topical retinoids as second-line therapy for the treatment of flat warts.’. Second Line Support means the identification, diagnosis and correction of Errors by the provision of (a) telephone and email assistance by a qualified individual on the Contact List and remote application support, or (b) on-site technical support at the State's premises … "We gonsecond line Soulja Slim" -B.G. Many of our technicians have over five years of experience, offering extensive experience working on … adj. Before we continue, here is my interpretation of ITIL Incident and Incident management definition: An Incident is, by definition, any unplanned service degradation or interruption, and within ITIL best practices framework  Incident Management is responsible for incident identification, logging and categorization, with the primary goal being a quick-as-possible restoration of service. Each of these cell types has a specific function, but they all work together to protect you.NeutrophilsThese cells primarily attack bacteria. So, second-line agents are those that handle escalations, difficult customers and technical queries. Second Lines for Weddings As it is a celebration, second-lines are a popular tradition among New Orleans weddings. Search second line and thousands of other words in English definition and synonym dictionary from Reverso. Our second-line technicians are certified through NCR University training on NCR ATMs. They rush to the site of incoming bacteria to fight them, but are easily killed. Our coverage has been unique and has been widely proliferated on the web and in print media. you can see these people (marching bands) play music with instruments such as trumpets, saxaphoneetc goin ina parade after someone dies. second-line definition in English dictionary, second-line meaning, synonyms, see also 'second wind',second fiddle',second language',second lieutenant'. Enrich your vocabulary with the English Definition dictionary second line in American English. Learn more. For nearly a decade, Second Line of Defense has been providing cutting edge interviews with warfighters and the teams that support them. Relating to or being a secondary stage of something: the body's second-line defense against infection. Second line is a tradition in brass band parades in New Orleans, Louisiana. This is a key point in the difference between first and second line support. The compliance and risk functions may have their own management and governance committees that are part of the ERM framework, or they may have direct reporting lines into appropriate ERM framework structures. {{#verifyErrors}} {{message}} {{/verifyErrors}} {{^verifyErrors}} {{#message}} Our interviews have been conducted worldwide and have focused on the evolution and transformation of the defense capabilities of the liberal democracies. second line. ; adjective Of or relating to second-line jazz. second-liners definition: → secondaries. ‘No ideal second-line treatment has been established if the initial therapy fails to eradicate the organism.’ ‘These differences in second-line therapy may account for some part of the observed difference in survival.’ ‘Endometrial curettage may be used as a second-line treatment if pharmacological efforts have been ineffective.’ The first line is usually a brass band and the ones being honored, the newlyweds. The "main line" or "first line" is the main section of the parade, or the members of the actual club with the parading permit as well as the brass band. This type of therapy may be aimed at improving quality of life and reducing cancer-related symptoms. They don’t use their time for queries that anyone can answer. a jaunty, syncopated rhythm in 2/4 time, often used in the rhythm and blues and jazz of New Orleans. a jazz marching band. The second line of defence is the enterprise’s compliance and risk functions that provide independent oversight of the risk management activities of the first line of defence. More example sentences. a picture stuck onto wood or cardboard and cut into pieces of different shapes that must be joined together correctly to form the picture again First-line antituberculosis drugs- Isoniazid (INH), rifampicin (RIF), ethambutol (EMB), pyrazinamide (PZA) and streptomycin (SM). Your second payment is still on the evolution and transformation of the English,... 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